Simulations Meet Experiment to Reveal New Insights into DNA Intrinsic Mechanics
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چکیده
منابع مشابه
Simulations Meet Experiment to Reveal New Insights into DNA Intrinsic Mechanics
The accurate prediction of the structure and dynamics of DNA remains a major challenge in computational biology due to the dearth of precise experimental information on DNA free in solution and limitations in the DNA force-fields underpinning the simulations. A new generation of force-fields has been developed to better represent the sequence-dependent B-DNA intrinsic mechanics, in particular w...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2015
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1004631